生物晶片製造及其方法Method for fabricating a biosensor chip and the biosensor chip made thereby

專利類型

發明

專利國別 (專利申請國家)

美國

專利申請案號

13/854,847

專利證號

US 9,091,683 B2

專利獲證名稱

生物晶片製造及其方法Method for fabricating a biosensor chip and the biosensor chip made thereby

專利所屬機關 (申請機關)

國立中興大學

獲證日期

2015/07/28

技術說明

一種生化感測晶片基板及其製法，該感測晶片基板包含一基材、分別設置於該基材上的一奈米粒子單元及一感測單元。該基材由可透光的材質所製成，該奈米粒子單元包括多數個相間隔地形成 於該基材一表面的金屬奈米粒子，該感測單元包括多數個修飾在該基材上，並位於該等金屬奈米粒子之間且鄰近該等金屬奈米粒子的接收器。當該感測單元的接收器與目標分析物形成專一性接 合時，金屬奈米粒子誘發的局部性電磁場會受週遭環境影響而變化，並導致光譜訊號變化，藉此能偵測目標分析物，使本發明具有發展為生化感測工具的實用價值。 A biochemical sensing wafer substrate manufacturing method thereof, the sensing wafer substrate includes a substrate, respectively, set in a sub-unit of the nanoparticles on the substrate, and a sensing unit. The substrate can be made ​​of transparent material, the nanoparticles formed unit includes a plurality of spaced several places On a surface of the substrate metal nanoparticles, the sensing unit includes a plurality of several modifications on the substrate, and is located close to those of the metal and metal nanoparticles receiver between nanoparticles. When the receiver with the target analyte to form the sensing means connected to specific Timely, metal nanoparticles induced localized electromagnetic field surrounding environment will be affected by the change and lead to changes in the signal spectrum, thereby able to detect target analytes, with the development of the present invention as biochemical sensing tools and practical value.

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本部(收文號1050015605)同意該校105年3月2日興產字1054300176號函申請同意專利讓與

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