微陣列壓印技術將生醫檢體置於生化鍵結表面Micro-fabricated stamp array for depositing biologic diagnostic testing samples on bio-bindable surface

專利類型

發明

專利國別 (專利申請國家)

美國

專利申請案號

12/006,939

專利證號

US 8,133,455 B2

專利獲證名稱

微陣列壓印技術將生醫檢體置於生化鍵結表面Micro-fabricated stamp array for depositing biologic diagnostic testing samples on bio-bindable surface

專利所屬機關 (申請機關)

國立清華大學

獲證日期

2012/03/13

技術說明

本發明係提供一種流體微米陣列晶片組，其係包含一微陣列填充晶片及一微陣列壓印晶片。該微陣列填充晶片上方設有複數個檢體儲槽及複數個奈微流道，其下方另設有奈微米等級的複數個微填充孔。各該奈微流道連接一該檢體儲槽，並將各該檢體儲槽中檢體溶液導引到對應之該微填充孔。該微陣列壓印晶片包含呈陣列狀排列複數個壓印頭、壓印晶片本體及形成疏水區之複數個間隔流道，該壓印晶片本體可分別儲存該複數個檢體溶液，並由該複數個壓印頭將對應之該檢體溶液導引至各該壓印頭之壓印部。藉由微陣列壓印頭，平行同時將數百個檢體微液珠蓋印至有化學處理過的表面形成微陣列晶片。 The present invention discloses micro-stamp array supported on a substrate comprising a plurality of micro-stamp sticks. Each of the micro-stamp sticks includes a micro-stamp-stick head having a channel opened through a central portion in each of the micro-stamp sticks. Each of the micro-stamp-stick heads is attached to a tapered guide tube surrounded by tapered guide-tube walls wherein the tapered guide tube is in hydraulic communication with the micro-stamp-head channel. The micro-stamp array further includes a filler chip that includes a filler reservoirs disposing on top of the tapered guide tubes, each of the filler reservoirs having a refill channel opened to the tapered guide tube for refilling the tapered guide tube and the channels.

備註

連絡單位 (專責單位/部門名稱)

智財技轉組

連絡電話

03-5715131-62219

網址