發明
中華民國
103128566
I 536009
檢測金屬離子濃度之方法及系統METHOD AND SYSTEM OF METAL IONS DETECTION
國立中興大學
2016/06/01
本發明係有關於一種檢測金屬離子濃度之方法,包括:提供一含金屬離子之樣品及一檢測試劑,其中檢測試劑係包含生物分子及金奈米粒子;將樣品及檢測試劑混合以得到一混合物,其中樣品中之金屬離子係與生物分子結合,以使金奈米粒子產生不同程度的聚集,產生不同的顏色變化;將混合物轉移至一微流試紙上;以及以一封閉工作平台偵測轉移有混合物之微流試紙,其中封閉工作平台包括一光源、一偵測單元及一輸出單元,光源照射微流試紙,偵測單元偵測經光源照射後之微流試紙之一顏色訊號,且輸出單元將顏色訊號以一數值方式輸出;本發明亦有關於一種檢測樣品中金屬離子濃度之系統。 The invention is related to a method of metal ions detection, which comprises: providing a sample with metal ions and a detect agent, wherein the detect agent comprises a plurality of biological molecules and a plurality of gold nanoparticles; blending the sample and the detect agent to form a mixture, wherein the metal ions incorporate into the biological molecules, and causes the different degrees of gold nanoparticles aggregation; transferring the mixture to a paper-based analytical platform; and the paper-based analytical platform is disposed in an enclosed working platform which is used for detecting the metal ions, wherein the enclosed working platform comprises a light source, a detect unit and a output unit, the light source irradiate the paper-based analytical platform, the detect unit captures the signal of color change of the paper-based analytical platform, and the output unit exports the signal of color change in the form of numerical data.
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