發明
中華民國
105142131
I 639436
藥物載體及其製造方法
國立清華大學
2018/11/01
本發明提供一種藥物載體及其製造方法。上述藥物載體用於包覆含硼藥物。上述藥物載體包括:帶負電多糖內核以及帶正電多醣外殼。帶負電多糖內核包覆含硼藥物。帶正電多醣外殼包覆帶負電多糖內核的表面。上述藥物載體可傳送並聚集至腫瘤組織附近,且在傳送過程中含硼藥物的洩漏低,以降低對正常細胞的傷害。A drug carrier and a method of fabricating the same are provided. The drug carrier is used to cover boron-containing drugs. The drug carrier includes a negatively charged polysaccharide inner core and a positively charged polysaccharide outer shell. The negatively charged polysaccharide inner core covers the boron-containing drugs. The positively charged polysaccharide outer shell covers a surface of the negatively charged polysaccharide inner core. The drug carrier can be transferred and gathered near a tumor tissue. Also, a leakage of the boron-containing drugs in the transfer process is low, so as to reduce damage of normal cells.
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