單離的胜肽、含彼之抗癌醫藥組成物及其用於專一性降低或抑制癌細胞活性的方法ISOLATED PEPTIDE, ANTI-CANCER MEDICINAL COMPOSITION INCLUDING THE SAME AND METHOD OF SPECIFICALLY REDUCING OR INHIBITING ACTIVITIES OF CANCER CELLS USING THE SAME

專利類型

發明

專利國別 (專利申請國家)

美國

專利申請案號

17/096,463

專利證號

US 11,396,529 B2

專利獲證名稱

單離的胜肽、含彼之抗癌醫藥組成物及其用於專一性降低或抑制癌細胞活性的方法ISOLATED PEPTIDE, ANTI-CANCER MEDICINAL COMPOSITION INCLUDING THE SAME AND METHOD OF SPECIFICALLY REDUCING OR INHIBITING ACTIVITIES OF CANCER CELLS USING THE SAME

專利所屬機關 (申請機關)

國立中山大學

獲證日期

2022/07/26

技術說明

【中文】 本發明有關於一種單離胜肽、含彼之醫藥組成物及其用於專一性減少或抑制癌細胞活性的方法。前述單離胜肽包含第一型人類免疫缺乏病毒TAT (HIV-1 TAT)鹼性結構域共軛至γ-胺基丁酸受體相關樣蛋白2 α-螺旋2 (GABARAPL2 H2)結構域，可專一性減少或抑制癌細胞活性，藉此應用至抗癌醫藥組成物及其用於專一性減少或抑制癌細胞活性的方法。 【英文】 The present invention relates to an isolated peptide, an anti-cancer medicinal composition including the same and a method of specifically reducing or inhibiting activities of cancer cells using the same. The isolated peptide including a TAT basic domain conjugated to a GABARAPL2 H2 domain can specifically reduce or inhibit an activity of cancer cells, thereby being applied to the anti-cancer medicinal composition and the method of specifically reducing or inhibiting activities of cancer cells using the same.

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