使用螢光顯微影像的老鼠誘發性多功能幹細胞生成之偵測與定位/細胞の再プログラム化を検出するための方法及び装置

專利類型

發明

專利國別 (專利申請國家)

日本

專利申請案號

特願 2017-026477

專利證號

特許 6931870

專利獲證名稱

使用螢光顯微影像的老鼠誘發性多功能幹細胞生成之偵測與定位/細胞の再プログラム化を検出するための方法及び装置

專利所屬機關 (申請機關)

中原大學

獲證日期

2021/08/19

技術說明

Induced pluripotent stem (iPS) cells are pluripotent cells generated from differentiated cells. Cells, such as fibroblasts, are induced into a pluripotent state by introducing genes encoding specific transcription factors into cells using viral vectors, adenovirus, plasmids, and naked DNA. iPS cells present an ideal source for patient-specific cell-based regenerative medicine because potential issues of allogeneic immune rejection can be avoided. [0006] iPS cells have been established from various mammalian cells including human cells and successfully induced into differentiated cells to make tissues or organ-like structures in vitro. Currently, clinical studies and trials, such as iPS cell-derived retinal pigment epithelium, have been initiated. To foster practical medical uses of iPS cells, large-scale expansion of iPS cells and methods for correcting possible mutations occurring during the iPS formation are urgently pursed. [0006] iPS cells have been established from various mammalian cells including human cells and successfully induced into differentiated cells to make tissues or organ-like structures in vitro. Currently, clinical studies and trials, such as iPS cell-derived retinal pigment epithelium, have been initiated. To foster practical medical uses of iPS cells, large-scale expansion of iPS cells and methods for correcting possible mutations occurring during the iPS formation are urgently pursed.

備註

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