一種調控細胞生長的方法Method for regulating proliferation of cells

專利類型

發明

專利國別 (專利申請國家)

美國

專利申請案號

12/155,488

專利證號

US 8,426,196 B2

專利獲證名稱

一種調控細胞生長的方法Method for regulating proliferation of cells

專利所屬機關 (申請機關)

國立成功大學

獲證日期

2013/04/23

技術說明

本發明係提供一種用以調控細胞生長的方法，其包含：將含有細胞的培養物培養於一第一培養系統中，其中該第一培養系統包括一培養載體以及一細胞外基質組份，該培養載體具有一表面，而該細胞外基質組份係塗布於該培養載體的表面；收集經培養的細胞而形成一含有細胞的培養物；以及將含有細胞的培養物培養於一第二培養系統中，其中該第二培養系統包括一培養載體以及一含有一細胞外基質組份的培養基，該含有細胞外基質組份的培養基係容置於該培養載體上。本發明之方法可以於活體外藉由延緩細胞生長速率以及促進細胞生長速率來調控細胞之生長。 A method for regulating proliferation of cells, has steps of providing a first culture system with a surface that is coated with a biological material; inoculating and culturing cells on the surface of the first culture system in an appropriate medium, such that the proliferation of the cells is preserved; collecting the cells; providing a second culture system with a surface; and inoculating and culturing the cells on the surface of the second culture system in a culture medium containing the biological material, such that the proliferation of the cells is promoted. A method for regulating proliferation of cells is also provided, the method being the same as the previous method except that the step of inoculating and culturing in a first culture system is performed before the step of inoculating and culturing in a second culture system.

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