細胞檢測方法

專利類型

發明

專利國別 (專利申請國家)

中華民國

專利申請案號

107115775

專利證號

I 662123

專利獲證名稱

細胞檢測方法

專利所屬機關 (申請機關)

國立清華大學

獲證日期

2019/06/11

技術說明

一種細胞檢測方法，包括：提供感測裝置，感測裝置包括基體以及至少一反應電極，反應電極相對於基體的閘極端而與基體彼此間隔設置。將包含目標細胞的待測溶液放置於反應電極上，施加第一脈波電壓於反應電極，並量測自基體產生的第一檢測電流。改變目標細胞的膜電位，並施加第二脈波電壓於反應電極，並量測自基體產生的第二檢測電流，其中第一檢測電流與第二檢測電流的正負值相反。 A method of sensing cells is provided. The method includes the following steps. A sensing device including a base and at least one response electrode is provided, wherein the response electrode is spaced apart from a gate end of the base. A test solution containing target cells is placed on the response electrode, a first pulse voltage is applied to the response electrode, and a first detection current generated from the base is measured. Membrane potential of the target cells is changed, a second pulse voltage is applied to the response electrode, and a second detection current generated from the base is measured, wherein a sign of the first detection current and a sign of the second detection current are opposite.

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