發明
美國
12/914,796
US 8,258,469 B2
旋轉式電噴灑游離裝置、質譜儀,以及質譜分析方法CYCLING ELECTROSPRAY IONIZATION DEVICE
國立中山大學
2012/09/04
本説明是有關於一種旋轉式電噴灑游離裝置。該電噴灑游離裝置包含著一能繞著一中心軸線旋轉的旋轉機構;以及至少一與該中心軸線相間隔地安裝在該旋轉機構上的噴嘴,該噴嘴能圍繞著一旋轉中心旋轉,而行成一封閉型的移動軌跡,以使得該噴嘴是在循著移動軌跡旋轉時,同時的噴灑出電噴灑液滴。本發明還提供一種質譜儀,以及一種質譜分析方法。本發明噴嘴循一儀動軌跡旋轉式地噴灑出電噴灑液滴,使得電噴灑出的每一帶電粒子(液滴)於噴灑空間均勻分布,克服帶電粒子彼此互相排斥的空間電荷效應,使得電噴灑形成的多數微小帶電粒子流進入質譜儀中的質量分析器入口的數目與比例增加,不只能提高離子訊號的穩定及強度,也能有效提升質譜分析的靈敏度。 This invention provides a rotating electrospray ionization device adapted for use in a mass spectrometer which includes a mass analyzer and a detector. The rotating electrospray ionization device comprises a rotating apparatus that is rotating around a pivotal line, and at least one nozzle disposed on the rotating apparatus . Each nozzle is set apart from the pivotal line and can rotate around a rotating center to form an enclosed-shape motion locus. And a locus zone formed by projecting the motion locus along the pivotal line onto a defined vertical plane perpendicular to the pivotal line is at least partially overlapped with an incidence zone formed by projecting the circumference of the entrance of the analyzer along the pivotal line onto the defined vertical plane. The invention also discloses a mass spectrometer and a method for mass spectrometry.
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