發明
中華民國
110128774
I 775554
肺呼吸晶片與細胞拉伸培養平台及其運作方法
國立清華大學
2022/08/21
本發明揭露一種肺呼吸晶片與細胞拉伸培養平台及其運作方法。肺呼吸晶片與細胞拉伸培養平台係透過程式編寫控制馬達輸出、利用凸輪元件對微流體晶片進行拉伸、改變凸輪元件的尺寸及馬達轉動的頻率來改變拉伸頻率及拉伸量,以模擬不同狀態下的肺部呼吸情況、透過液體介電泳技術對生物相容性水膠及水膠中的細胞進行三維排列,以仿造出三維的細胞組織、以及透過動態灌流系統灌流藥物,以實現晶片仿生肺組織中細胞受到拉伸時的藥物測試平台。 A lung breathing chip and cell stretching culture platform and an operating method thereof are disclosed. The lung breathing chip and cell stretching culture platform controls the output of the motor by programming, stretches the micro-fluidic chip by the cam component, changes the size of the cam component and the frequency of the motor rotation to change the stretching frequency and the amount of stretching to simulate the breathing of the lungs in different states, uses liquid electrophoresis technology to arrange the cells in the biocompatible water gel and the water gel three-dimensionally to imitate the three-dimensional cell tissue, and injects drugs through the dynamic perfusion system to realize the drug testing platform that the cells of the chip bionic lung tissue are stretched.
智財技轉組
03-5715131-62219
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