收集類澱粉蛋白的系統、其用途及移除類澱粉蛋白的方法

專利類型

發明

專利國別 (專利申請國家)

中華民國

專利申請案號

109101106

專利證號

I 725702

專利獲證名稱

收集類澱粉蛋白的系統、其用途及移除類澱粉蛋白的方法

專利所屬機關 (申請機關)

國立清華大學

獲證日期

2021/04/21

技術說明

本發明提供一種收集類澱粉蛋白的系統包含一反應槽、至少一奈微米磁棒、一旋轉磁場供應裝置以及一驅動裝置。反應槽包含複數個吞噬細胞。旋轉磁場供應裝置用以提供一旋轉磁場至反應槽。當旋轉磁場供應裝置受驅動裝置驅動並於反應槽提供旋轉磁場時，奈微米磁棒將受旋轉磁場驅動而於反應槽中自轉，而反應槽中的樣本將對應奈微米磁棒的自轉而產生一微漩渦流以使類澱粉蛋白聚集，並在後續為吞噬細胞捕捉。藉此，本發明之收集類澱粉蛋白的系統可在不破壞樣本的前提下透過吞噬細胞溫和地移除與代謝其中的類澱粉蛋白，並具有相關市場的應用潛力。 The present disclosure provides a system for collecting amyloid including a reaction tank, at least one nano-micro magnetic stir bar, a rotating magnetic field supply device and a driving device. The reaction tank includes a plurality of phagocytes. The rotating magnetic field supply device is used to provide a rotating magnetic field to the reaction tank. When the rotating magnetic field supply device is driven by the driving device and provides the rotating magnetic field to the reaction tank, the nano-micro magnetic stir bar will be driven by the rotating magnetic field so as to rotate in the reaction tank, and a micro-whirlpool flow of a sample in the reaction tank will be generated corresponding to the rotation of the nano-micro magnetic stir bar. Thus, the amyloid will be gathered and captured by the phagocytes later. Therefore, the system for collecting amyloid of the present disclosure can gently remove and metabolite the amyloid by the phagocytes without destroying the sample and can have potential to apply in the relevant market.

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