灌流式細胞培養裝置及灌流式細胞培養系統

專利類型

發明

專利國別 (專利申請國家)

中華民國

專利申請案號

110107796

專利證號

I 780616

專利獲證名稱

灌流式細胞培養裝置及灌流式細胞培養系統

專利所屬機關 (申請機關)

國立清華大學

獲證日期

2022/10/11

技術說明

本發明提供一種灌流式細胞培養裝置，其包含一驅動模組以及複數個細胞培養模組。驅動模組包含一驅動源出入口及一腔室，而腔室連通驅動源出入口。各細胞培養模組包含一流體流道、一第一彈性元件、二流向控制單元及一細胞培養區。流體流道設置於腔室上方，第一彈性元件設置於流體流道與腔室之間。二流向控制單元分別設置於流體流道的二端並與流體流道選擇性地連通，而細胞培養區連接二流向控制單元。藉此，本發明之灌流式細胞培養裝置僅需使用單一驅動源即可進行多組之灌流式細胞培養，不但能實現高通量化且有助於精簡系統規模。 The present disclosure provides a perfusion cell culture device. The perfusion cell culture device includes a driving module and a plurality of cell culture modules. The driving module includes an opening for connecting a driving source and a chamber. The opening and the chamber are connected. Each of the cell culture modules includes a fluid channel, a first elastic element, two flow direction controlling units and a cell culture zone. The fluid channel is disposed above the chamber. The first elastic element is disposed between the fluid channel and the chamber. The two control units are disposed on two ends of the fluid channel respectively and connect the fluid channel. The cell culture zone connects the two control units. Thus, the perfusion cell culture device of the present disclosure can perform multiple sets of perfusion cell culture by a single driving source that is favorable to achieve high throughput and simplify the system scale.

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