細胞貼附裝置以及該細胞貼附裝置之製造方法

專利類型

發明

專利國別 (專利申請國家)

中華民國

專利申請案號

107104055

專利證號

I 662125

專利獲證名稱

細胞貼附裝置以及該細胞貼附裝置之製造方法

專利所屬機關 (申請機關)

中原大學

獲證日期

2019/06/11

技術說明

(1)中文 本發明提供一種細胞貼附裝置及方法，其係於一基板的一表面，形成一細胞吸附層，再於該細胞吸附層的表面形成具有複數個溫感高分子的一磁性溫感層，每一溫感高分子係具有複數個磁性粒子。當該磁性溫感層於一交變磁場作用時，使得複數個細胞得以附著於該細胞吸附層上。透過本發明的細胞吸附裝置可以在先以控制溫度至一第一溫度誘使基板上的溫感高分子產生結構變化，使細胞貼附於該細胞吸附層上。另以交變磁場(HAC)對使溫感高分子內的磁性粒子溫升，使細胞能於低於該第一溫度的一第二溫度維持細胞貼附的效果。 (2)英文 The present invention provides a device and method for culturing cells, wherein a cell culturing layer is formed on a surface of a substrate, and a temperature-responsive layer having a plurality of temperature-responsive polymer with magnetic particles is formed on a surface of the cell culturing layer. When an external alternating magnetic filed (HAC) is exerted on the temperature-responsive layer a plurality of cells can be adhered on the cell culturing layer. When the device is utilized, a temperature control step is operated to control environmental temperature at a first temperature for inducing temperature-responsive polymers becoming hydrophobic whereby the plurality of cells are adhered on the cell culturing layer. In addition, the alternating magnetic field is utilized to rise temperature of the temperature-responsive polymers so that the plurality of cells can be kept being adhered on the cell culturing layer at a second temperature lower than the first temperature.

備註

連絡單位 (專責單位/部門名稱)

產學合作暨專利技轉中心

連絡電話

(03)2651830

網址